I've also been using Sql Litespeed on several boxes backing up around a terabyte of data across all servers. I had some issues with the older 3.0.123 and up untill the new 3.1.x versions all of that is running very well. All my backup and restore scripts are centered around litespeed as well. I don't use maint plans or the gui that ships with SLS at all. I will say the new gui is much much better than the last one was. We are averaging 8:1 compression and at least a 75% reduction in backup times and around 15% reduction in restore times.

Wes