You will be covered. Hotfixes are generally cumulative.
Per Microsoft: "Unless otherwise specified, all the hotfixes in earlier builds are included in later builds."
This information is from the MS knowledge base article 894905: Cumulative list of the hotfixes that are available for SQL Server 2000 SP4
http://support.microsoft.com/kb/894905/
-- J.Kozloski, MCDBA, MCITP